|
Test ID: Parvovirus B19 Antibody IgG
|
|
Parvovirus B19 Antibody IgG
|
|
Detection of Parvovirus B19 IgG Antibody in Blood
|
|
Useful For
|
Determination of specific IgG antibodies to parvovirus B19 in human serum or plasma samples.
|
|
Method name and description
|
Indirect sandwich chemiluminescence immunoassay (CLIA)
In the presence of complimentary antigen and antibody, the antibody binds to the antigen to form an antigen-antibody or an immune complex.The light signal, the amount of isoluminol-antibody conjugate, is measured by a photomultiplier as relative light units (RLU) and is indicative of analyte concentration present in calibrators, samples or controls.
|
|
Clinical information
|
Parvovirus B19 infection is normally acquired by direct contact with respiratory secretions and normally occurs in localized outbreaks during the winter and spring months. It is now accepted that seronegative women are susceptible to parvovirus B19 infection. The majority of pregnancies during which parvovirus B19 infection occurs result in delivery of a healthy foetus at term. However, infection during pregnancy presents the risk of transmission to the foetus which may result in hydrops foetalis or intrauterine death. It is causative agent of a number of clinical conditions such as rash, arthralgia and foetal damage. Consequently, it is important to identify the parvovirus B19 antibody status in individuals who may be at risk of infection from, or who have been infected with, parvovirus B19.
|
|
Aliases
|
Parvovirus B19 Antibody IgG
|
|
|
Specimen type / Specimen volume / Specimen container
|
Specimen type: Serum, Plasma
Minimum volume of sample: 1 mL
Serum: Plain tube (red or yellow top)
Plasma: Heparin tube
|
|
Collection instructions / Special Precautions / Timing of collection
|
Collect blood by standard venipuncture techniques as per specimen requirements. When processing samples in primary tubes (sample collection systems), follow the instructions of the tube manufacturer.
|
|
Storage and transport instructions
|
Storage: 3 days at 2 – 8°C;
Transport: 2-25°C
|
|
Specimen Rejection Criteria
|
Grossly hemolyzed, icteric and lipemic samples, wrong collection container, insufficient samples.
|
|
|
Biological reference intervals and clinical decision values
|
|
Analyte/Unit
|
Result message
|
Result message
|
Interpretation/ further steps
|
|
Index
|
< 0.9
|
Negative
|
Negative for Parvovirus B19 IgG, no further testing needed.
|
|
Index
|
≥ 0.9 to < 1.1
|
Equivocal
|
Equivocal samples should be verified as equivocal & comment will be added automatically by system.
|
|
Index
|
≥ 1.1
|
Positive
|
Positive for Parvovirus B19 IgG, no further testing
|
|
|
Turnaround time / Days and times test performed / Specimen retention time
|
Daily (24/7)
Turn-around time:
Routine: One working day
Specimen Retention: 4 days
|
|
|
