Lab Guide
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Test ID: Oxalate (24h urine)
Oxalate (24h urine)
Oxalate (24h urine)
Useful For

The investigation and monitoring of renal stone formers

Method name and description

Enzymatic reaction

Clinical information

Oxalate is a poorly soluble anion and high concentrations of in the urine is a risk factor for the formation of renal calculi.  A group of inherited diseases (primary hyperoxalurias) can result in elevated oxalate concentrations due to aberrant glyoxylate or glycerate metabolism.

Aliases

Oxalic acid

Specimen type / Specimen volume / Specimen container

Specimen type: urine, 24 hours collection.

Specimen volume: total urine volume collected in 24 hours.

Specimen container: suitable 24 hours plain urine collection container/s.

 

 

Collection instructions / Special Precautions / Timing of collection

Avoid intake of oxalate rich food, like spinach, chocolate, rhubarb, or oxalate precursors such as vitamin C (Ascorbic Acid) for at least 48 hours before collection. Pyridoxine is said to diminish oxaluria. The patient should be on usual fluid and food intake.

Relevant clinical information to be provided

Presenting clinical signs and symptoms

Any relevant medications

Storage and transport instructions

Transport Temperature: 2 - 30 °C.

Storage Temperature: -20°C after add the preservative for upto 7 days.

The sample should not be thawed till analysis.

Specimen Rejection Criteria

Insufficient specimen quantity.

Biological reference intervals and clinical decision values

0.04 - 0.460 mmol/24h.

Factors affecting test performance and result interpretation

High levels of ascorbate (vitamin C) can lead to artefactual increases in oxalate

Turnaround time / Days and times test performed / Specimen retention time

Turnaround time: 5 working days.

Days and times test performed: Once a week.

Specimen retention time: 7 days.