Lab Guide
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Test ID: Albumin
Albumin
Useful For

Monitoring individuals dietary supplementation and diagnosis of liver of liver and kidney disorder.

Method name and description

Colorimetric test

At the reaction pH, BCP binds selectively with albumin, causing a color change that is measured photometrically.

Reporting name

Albumin

Clinical information

Albumin is a carbohydrate free protein, which constitutes 55 – 65 % of total plasma protein. It maintains plasma oncotic pressure, and is also involved in the transport and storage of a wide variety of ligands and is a source of endogenous aminoacids.

Hyperalbuminemia is of little diagnostic significance except in the case of dehydration.

Hypoalbuminemia occurs during many illnesses and is caused by several factors:

  • Compromised synthesis due to either liver disease or as a consequence of reduced protein uptake;
  • Elevated catabolism due to tissue damage (severe burns) or inflammation; Malabsorption of aminoacids (Crohn’s disease); Proteinuria as a consequence of nephrotic syndrome;
  • Protein loss via the stool (neoplastic disease).
Specimen type / Specimen volume / Specimen container

Specimen type: Serum, Plasma

Minimum volume of sample: 1 mL

Serum: Plain tube (red or yellow top)

Plasma: Li‑heparin tube

Collection instructions / Special Precautions / Timing of collection

If possible, the patient should be recumbent for at least 1 hour preceding specimen collection. Erect posture causes a redistribution of body fluids, increasing the serum albumin concentration.

Do not use citrate or oxalate tubes

Storage and transport instructions

Storage: 2.5 months at 20 – 25°C

              5 months at 4 – 8°C

               4 months at ‑20 °C (± 5 °C)

Transport: 4-25°C 

Specimen Rejection Criteria

Grossly hemolyzed, icteric and lipemic samples, wrong collection container, insufficient sample.

Biological reference intervals and clinical decision values

Patient Sex

Age Range

Range (g/L)

Female/Male

0 to 1 year

30-45

Female/Male

1 to 16 years                   

30-50

Female/Male

16 to 150 years               

35-50

Turnaround time / Days and times test performed / Specimen retention time

Daily (24/7)

Turn-around time

STAT: 1 hour

Routine: one working day

Specimen retention: 4 days