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Test ID: B‐Cell Acute Lymphoblastic Leukemia Panel by FISH
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B‐Cell Acute Lymphoblastic Leukemia Panel by FISH
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B‐Cell Acute Lymphoblastic Leukemia performed for analysis by FISH Test.
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Method name and description
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Interphase Fluorescence In Situ Hybridization (IFISH) Study
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Clinical information
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B-Acute Lymphoblastic Leukemia (ALL) is a disorder of B lymphoblast that accounts mostly in children with acute leukemia and a fraction of adults with acute leukemia.
B-ALL is broadly categorized as either having repetitive hereditary variations from the norm or not having repetitive hereditary variations. Repetitive hereditary variations from the norm incorporate both balanced translocations and aneuploidy. This FISH panel is used to distinguish the foremost common, and/or prognostically critical abnormalities in B-ALL.
FISH studies are valuable aids to total chromosome studies, especially when taken after an abnormal clone, assessing relapse and progression. This also serves as an aide to conventional chromosome studies.
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Specimen type / Specimen volume / Specimen container
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Specimen Type: Blood/Leukemic Blood:
Container/Tube: Green top (sodium heparin)
Specimen Volume: 2-6 mL (Varies depending on the WBC-Count)
(Adult - 3-6 mL ,Child - 2 mL, Infant - 2 mL)
Specimen Type: Bone marrow:
Container/Tube: Bone Marrow Transport Media
Specimen Volume: 1-3 mL (Varies depending on the WBC-Count)
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Storage and transport instructions
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Specimen Rejection Criteria
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Consistent with Diagnostic Genomic Division policies.
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Factors affecting test performance and result interpretation
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B-ALL is broadly categorized as either having repetitive genetic abnormalities or not; repetitive hereditary abnormalities incorporate both balanced translocations and aneuploidy.
This FISH panel is outlined to identify the foremost common, and/or prognostically-significant abnormalities in B-ALL.
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Turnaround time / Days and times test performed / Specimen retention time
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