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Clinical Trials at HMC

Clinical trials at HMC are your opportunity to be at the forefront of medical breakthroughs. Clinical trials are carefully conducted research studies that explore new treatments, medications or interventions. These trials aim to bring innovative solutions to improve patient care through enhancing medical knowledge. The HMC Clinical Trial Unit (CTU) is dedicated to promoting and facilitating clinical trials.

For additional information about the CTU and ongoing clinical trials, please scan the QR code or contact:​


What are Clinical Trials?

Clinical trials are research studies conducted to evaluate medical, surgical or behavioral interventions in individuals. They are the main method researchers use to assess whether a new treatment or preventive measure, such as a drug, diet or medical device is safe and effective. Typically, these trials aim to determine if a new treatment offers better results or fewer side effects compared to current options.

Why to Participate in Clinical Trials?

Individuals choose to participate in clinical trials and studies for several reasons, including:

  • A desire to help advance medical knowledge that could benefit others in the future.
  • A wish to take a more proactive role in managing their own health.
  • The treatments they have tried for their condition were ineffective or no existing treatments are available for their issue.
  • Receiving a treatment that works for them.
  • Receiving specialized medical care at top-tier healthcare facility.
  • Gaining access to new treatments that are not yet available to the general public

On going Studies in Clinical Trial Unit Qatar

Study Title

Department

The Safety and long-Term Clinical Benefit of PCSK9i in addition to Statin therapy in patients with ST-Segment Elevation Myocardial Infarction. A Randomized, Open Label Study.

Cardiology

Effectiveness of Human Albumin for clinical outcome in aneurysmal Subarachnoid Hemorrhages: A randomized controlled (Hash) trial

Neurology

 

Approved Studies in HMC Qatar

Study Title

A randomized double-blind placebo-controlled proof of concept trial to assess the anti-epileptic effect of the food supplement alpha-lactoalbumin in patients with epilepsy

Prevention of pre-eclampsia using metformin: a randomized control trial (PREMET)

Beta Blocker Use In Traumatic Brain Injury Based On The High-Sensitive Troponin T Status: A Randomized Controlled Trial (BBTBBT)

Impact of Early Antibiotics on Non-Traumatic Out of Hospital Cardiac Arrest (OHCA)

Efficacy of mechanical knee traction from 90? knee flexion for patients with knee Osteoarthritis

A Prospective, Triple Blinded, Randomized Comparison Of Bilateral Transversus Abdominis Plane Block With And Without Dexamethasone Plus Intravenous Saline Or Dexamethasone For Laparoscopic Appendectomy In Adult Population

Oral or Intra Muscular Vitamin D2 Vs Oral or Intra muscular Vitamin D3 in treatment of vitamin D deficiency.

Effectiveness of a novel model of occupational therapy intervention in improving psychosocial wellbeing for patients in cardiac rehabilitation phase II

Randomized controlled trial assessing use of Vancomycin powder in craniotomy on wound infection rates

Effect of Human Plasma protein Transfusion with and without Crystalloids on Acid Base, Electrolytes and Tissue Perfusion during Major Liver Resection Surgeries

The Feasibility of combined Pectoral Nerves Block and Superficial Cervical Plexus Block for Insertion of Vascular Ports in the Lower Neck and Upper Chest Wall

The Effect of Obesity on Pharmacokinetic and Pharmacodynamic Disposition of Rivaroxaban

High-flow nasal Oxygen Therapy to prevent extubation failure in Adult Trauma Intensive Care patients

A prospective randomized study comparing flexible ureteroscopy and semirigid ureteroscopy for the treatment of proximal ureteral stone

A randomized, multicenter, open-label cross-over study to evaluate patient preference and satisfaction of subcutaneous administration of the fixed-dose combination of pertuzumab and trastuzumab in patients with her2-positive early breast cancer

Early Pregnancy Intervention for the Prevention of Gestational Diabetes Mellitus (PLEDGE)

The impact of obstructive sleep apnea treatment on diabetic microvascular complications: A randomized controlled trial

Nebulized Lidocaine and Intranasal Midazolam for Reducing Pain/Anxiety of Nasogastric Tube Insertion in Children: A Randomized Controlled Trial

A Randomized Clinical Trail Comparing the Effect of Vibration Cold (BUZZY) Device with EMLA cream in Decreasing the Needle-Related Pain and Anxiety in Pediatric Emergency Setting: a non-inferiority study.

A Randomised Clinical Trial To Evaluate The Clinical And Biological Effects Of Azithromycin Treatment For Preschool Children Admitted to Pediatric Unit with Acute Severe Wheeze.

Efficacy of corticosteroids in reducing the renal scarring in acute pyelonephritis in children ,randomized clinical trial

Radiofrequency versus coblator assisted turbinoplasty in cases of inferior turbinate hypertrophy: A randomized clinical study

Anticoagulation in patients suffering from COVID-19 disease-MRC-05-082

Flow controlled ventilation in ARDS associated with COVID-19-MRC-05-05-018

Effect of regular use of Hydrogen peroxide and chlorhexidine gluconate mixed solution for mouth wash and gargles, on the COVID19 recovery rate; a Randomized, controlled trial (MRC 05-106)

Comparative Study between Volume Controlled Ventilation and Flow Controlled Ventilation through Ultra-thin tube in Upper Airway Surgery

Orthopedic Wound Dressing Using Sterile Versus Clean Non-sterile Techniques At Hamad General Hospital.

Salbutamol versus hypertonic saline 3% nebulizer in acute bronchiolitis, Single center double blinded Randomized Control Trial

Thulium vs Low-power Holmium YAG lithotripsy: A Prospective, Randomized Single blinded Study in Patients Undergoing Flexible Ureteroscopy

Effect of Pioglitazone on Inflammatory Response and Clinical Outcome in Type 2 Diabetes Mellitus Patients with COVID-19

A Comparative study of supine position and the head elevated position on the level of sensory block after spinal anesthesia in morbidly obese parturient undergoing elective cesarean delivery --MRC-01-20-792

A Multicenter Randomized Controlled Trial Assessing the Efficacy of Antimicrobial Prophylaxis for Extracorporeal Shock Wave Lithotripsy on Reducing Urinary Tract Infection (APPEAL Trial)

Safety and Efficacy of BNT162b2 and mRNA-1273 RNA-Based COVID-19 Vaccines on Elderly Patients in Qatar: A Prospective Randomized Control Trial Study

Impact of Dietary and Physical Therapy Intervention on Sarcopenia in Falls Patients: An open label clinical trial Prevalence of Sarcopenia in Falls Patients and Impact of Dietary and Physical Therapy Intervention

Comparing of Surgicel NU-KNIT and Bone Wax and their impacts on median sternotomy wound infection and bleeding. Randomized Clinical Trial

Exploratory phase iia pilot trial for safety and efficacy of freeze-dried platelets (thrombosome) in injured patients requiring activation of the massive transfusion protocol

The impact of oestrogen administration on covid-19 disease progression and outcome (MRC-05-099)

Effectiveness of Enhanced stroke Upper Extremity Program (ESUP) During Inpatient Stroke rehabilitation: A Pilot Randomized Control Trail

Effect of technology-based intervention for executive function skill training on inpatients with traumatic brain injury with mild to moderate cognitive deficits: A Randomized Control Trial

Nurse-led medication self-management intervention in the improvement of medication adherence in adult patients with multimorbidity: A feasibility Randomized controlled trial

Development and Evaluation of a Multidisciplinary Team Delivered Deprescribing Intervention for Patients with Chronic Kidney Disease in Qatar: A Multi-Centered Randomized Controlled Trial

To develop and validate a structured exercise protocol and to assess its effectiveness in patients with subacromial impingement syndrome

The Effectiveness of Using Daily Living Skills and Sensory Integration Training Combined with Executive Function Strategies for Improving Self-Care, sensory integration and Fine Motor Skills in Children with ASD in Qatar: A Randomized Control Trial

Role of lung ultrasound in the assessment and management of pulmonary congestion in chronic hemodialysis patients: A Randomized controlled study

E-pause : Encouraging Proper Antibiotic Use in Outpatient Settings

Evaluating the impact of task specific training on functional outcomes in stroke patients

Development, Validation and Testing of an Education Program for Identification of Learning Disabilities among School Children by Primary School Teachers in Qatar

Effect of using Bio-RT on improving upper extremity movement among people with stroke: A Pilot open label Randomized Control Trial

Enhancing Post-Stroke Dysphagia Rehabilitation: The Synergistic Effects of Neuromuscular Electrical Stimulation, Neuromuscular Taping, and Swallowing Exercises: A randomized clinical blinded trial

Effects of early oral diet after cardiac surgery: an open label randomized controlled trial

Comparing the effectiveness of Hydrophilic Methacrylate Gel (Hemagel ?) and Beta Sitosterol Ointment in the Healing of Episiotomy and Cesarean Section Scars: A Randomized Controlled Trial"

Effectiveness of Botox injection for managing paratonia in moderate to severe dementia admitted in long term-care facilities: A randomized control trial

Efficiency of Thulium Fiber Laser versus Holmium YAG Laser in the treatment of ureteral stones: A prospective randomized pilot trial

Efficacy of adjuvant therapy in severe bronchospasm with vibrating mesh nebulizer vs. traditional nebulizer in reducing the rate of critical care admission and improving patient outcome

Efficacy of scalp block in managing post subarachnoid haemorrhage headache in critically ill patients. A Single Centre Randomized Controlled Trial.

Effectiveness of Return-To-Work multidisciplinary rehabilitation program on work status of individuals with subacute stroke .

Effect of Simulated Training of IADL on Occupational Balance and Occupational Performance Among Women with Stroke: A Pilot Randomized Control Trial

Pancreatic Stone Protein (PSP) as a Biomarker of Sepsis in Intensive Care Units: A Prospective Study

Fatty liver, Lifestyle And Glycaemia (FLAG) study: the impact of a low energy diet intervention on non-alcoholic fatty liver disease in type 2 diabetes mellitus

Using DNA-Typing and Erythrocyte Microparticle Analysis to Detect Blood Doping ? a Transfusion Study

CEFtolozane-Tazobactam for the Empiric Anti-bacterial Treatment of Neutropenic Fever in Hematology Patients; a Single-arm, Single-center, Open-label Clinical Trial (CEF-10 Study)

A phase III, randomized, open-label study evaluating the efficacy and safety of giredestrant in combination with phesgo versus phesgo after induction therapy with phesgo?taxane in patients with previously untreated her2-positive, estrogen receptor-positive locally-advanced or metastatic breast cancer

Prevention of Development of Diabetes in Those with Gestational Diabetes Mellitus - PROVIDE Trial

Diabetes Prevention for Early Onset Dysglycemia

Early Diabetes Intervention (EDIT)

Nanotechnology-based biosensor (diagnostic) for rapid detection of bacterial infection in biological fluids to monitor antibiotic resistance and reduce hospital acquired infections

Diabetes Intervention Accentuating Diet and Enhancing Metabolism (DIADEM-I): a randomized controlled trial assessing the impact of low calorie diet and activity on body weight and glycaemia in diabetes in early diabetes - 15395

Air Pollution and Cardiovascular disease In Qatar: an interventional study to reduce Blood Pressure: the APCIQ-BP trial

Randomized controlled trial to evaluate the efficacy of tobacco cessation treatment interventions among adult waterpipe smokers in Qatar